Voor velen is dit abracadabra. Maar wij zijn er zo ontzettend trots op, dat we dit allemaal in onze producten hebben kunnen toevoegen. Dat we voor dit een enkele fanatiekeling, niet willen ontnemen.


Cinnamon improves glucose and lipids of people with type 2 diabetes.

Cinnamon: Potential Role in the Prevention of Insulin Resistance, Metabolic Syndrome, and Type 2 Diabetes

Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis.

Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects.

Effects of a cinnamon extract on plasma glucose, HbA, and serum lipids in diabetes mellitus type 2.

In a study that compared the antioxidant activity of 26 spices, cinnamon wound up as the clear winner, even outranking “superfoods” like garlic and oregano: Antioxidant capacity of 26 spice extracts and characterization of their phenolic constituents

Chromium and polyphenols from cinnamon improve insulin sensitivity.

Cinnamon extract inhibits α-glucosidase activity and dampens postprandial glucose excursion in diabetic rats.

Inhibitory activity of cinnamon bark species and their combination effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase.

Cinnamaldehyde induces fat cell-autonomous thermogenesis and metabolic reprogramming

Effect of short-term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes.



Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

Antioxidant and anti-inflammatory properties of curcumin

The promise of slow down ageing may come from curcumin

When each system is optimized, you’ll find that your:
+ Food is properly digested
+ Bile production is balanced
+ Energy levels are higher
+ Feelings of fullness come easier
+ Calorie-burn rates are higher

Modulation of adipose tissue inflammation by bioactive food compounds

Curcumin: a natural product for diabetes and its complications

Curcumin and Diabetes: A Systematic Review

Curcumin Extract for Prevention of Type 2 Diabetes

The protective role of curcumin in cardiovascular diseases.

Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial.

Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials


Potential use of bitter melon (Momordica charantia) derived compounds as antidiabetics: In silico and in vivo studies.

Bitter Melon as a Therapy for Diabetes, Inflammation, and Cancer: a Panacea?

Medicinal Chemistry of the Anti-Diabetic Effects of Momordica Charantia: Active Constituents and Modes of Actions

Pharmacological actions and potential uses of Momordica charantia: a review

Systematic review of herbs and dietary supplements for glycemic control in diabetes

In vivo hypoglycemic effect of methanolic fruit extract of Momordica charantia L

Effectiveness of Antihyperglycemic Effect of Momordica charantia: Implication of T-Cell Cytokines

Beneficial Role of Bitter Melon Supplementation in Obesity and Related Complications in Metabolic Syndrome

Antidiabetic effects of Momordica charantia (bitter melon) and its medicinal potency

Momordica charantia Administration Improves Insulin Secretion in Type 2 Diabetes Mellitus

Hypoglycemic effect of bitter melon compared with metformin in newly diagnosed type 2 diabetes patients

Dietary supplementation of bitter gourd reduces the risk of hypercholesterolemia in cholesterol fed sprague dawley rats.

Effect of methanolic seed extract of Momordica charantia on body weight and serum cholesterol level of male Sprague-Dawley rats.

Wild bitter gourd improves metabolic syndrome: A preliminary dietary supplementation trial

The effects of Momordica charantia on obesity and lipid profiles of mice fed a high-fat diet

Results from the present study suggest that Momordica charantia extracts have anti-obesity effects and the ability to modulate lipid prolife of mice fed a HFD by suppressing body weight gain, visceral tissue weight, plasma and hepatic lipid concentrations, and lipid peroxidation along with increasing lipid metabolism.

Antioxidant potential of spices and their active constituents


Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress.

Piperine Promotes Glucose Uptake through ROS-Dependent Activation of the CAMKK/AMPK Signaling Pathway in Skeletal Muscle.

Piperine lowers the serum concentrations of thyroid hormones, glucose and hepatic 5’D activity in adult male mice.

Evaluation of the effect of piperine per se on blood glucose level in alloxan-induced diabetic mice.

Novel Piperine Derivatives with Antidiabetic Effect as PPAR-γ Agonists.

Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials.


[Chromium and insulin resistance].

Chromium as an essential nutrient for humans.

Chromium update: examining recent literature 1997-1998.

Chromium metabolism and its role in disease processes in man

Chromium in metabolic and cardiovascular disease.

Chromium in the prevention and control of diabetes

A scientific review: the role of chromium in insulin resistance.

Chromium, glucose tolerance, and diabetes.

Chromium Picolinate Supplementation Attenuates Body Weight Gain and Increases Insulin Sensitivity in Subjects With Type 2 Diabetes


Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes.


Glucose-lowering effect of fenugreek in non-insulin dependent diabetics.


Effect of fenugreek seeds on blood glucose and lipid profiles in type 2 diabetic patients.


Fenugreek bread: a treatment for diabetes mellitus.


A simple dietary addition of fenugreek seed leads to the reduction in blood glucose levels: A parallel group, randomized single-blind trial.


Fenugreek, diabetes, and periodontal disease: A cross-link of sorts!


A Review of the Hypoglycemic Effects of Five Commonly Used Herbal Food Supplements.


A Review of the Hypoglycemic Effects of Five Commonly Used Herbal Food Supplements.


The hypoglycaemic activity of fenugreek seed extract is mediated through the stimulation of an insulin signalling pathway


Hypolipidaemic Effect of Fenugreek Seeds: a Chronic Study in Non‐insulin Dependent Diabetic Patients.


Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit.


Therapeutic Effect of Fenugreek Seed on the Patients Suffering from Diabetes Mellitus type II.



Identification of cysteinylated transthyretin, a predictive biomarker of treatment response to partially hydrolyzed guar gum in type 2 diabetes rats, by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry

Improvement of the metabolic syndrome profile by soluble fibre – guar gum – in patients with type 2 diabetes: a randomised clinical trial.

Effect of partially hydrolyzed guar gum (PHGG) on the bioaccessibility of fat and cholesterol.

Effects of hydrolyzed guar gum on cholesterol and glucose in humans

Improvement of the metabolic syndrome profile by soluble fibre – guar gum – in patients with type 2 diabetes: a randomised clinical trial.

Effect of a modified guar gum preparation on glucose and lipid levels in diabetics and healthy volunteers

For all researches, see link below:


Magnesium Intake and Risk of Type 2 Diabetes in Men and Women

Magnesium metabolism in type 2 diabetes mellitus, metabolic syndrome and insulin resistance

Fiber and Magnesium Intake and Incidence of Type 2 Diabetes A Prospective Study and Meta-analysis

Magnesium intake and risk of type 2 diabetes: a meta‐analysis

Magnesium and insulin-dependent diabetes mellitus

Implications of Magnesium Deficiency in Type 2 Diabetes: A Review

The Effect of Magnesium Supplementation in Increasing Doses on the Control of Type 2 Diabetes

Role of dietary magnesium in cardiovascular disease prevention, insulin sensitivity and diabetes

Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta‐analysis of randomized double‐blind controlled trials

Vitamine B12

Vitamin B12 deficiency among patients with diabetes mellitus: is routine screening and supplementation justified?

Zittoun J, Zittoun R. Modern clinical testing strategies in cobalamin and folate deficiency. Sem Hematol 1999;36:35-46. [PubMed abstract]

Clarke R, Birks J, Nexo E, Ueland PM, Schneede J, Scott J, et al. Low vitamin B-12 status and risk of cognitive decline in older adults. Am J Clin Nutr 2007;86:1384-91. [PubMed abstract]


Willis MS et al. Zinc-induced copper deficiency: a report of three cases initially recognized on bone marrow examination. Am J Clin Pathol. 2005;123(1):125-31.

Prohaska JR. Copper. In: Erdman JW, Macdonald IA, Zeisel SH, eds. Present Knowledge in Nutrition. 10th ed. Washington, DC: Wiley-Blackwell; 2012:540-53.

Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academies Press; 2001.

Hellman NE, Gitlin JD. Ceruloplasmin metabolism and function. Annu Rev Nutr 2002;22:439-58. [PubMed abstract]


Fabris N, Mocchegiani E. Zinc, human diseases and aging. Aging (Milano) 1995;7:77-93. [PubMed abstract]

Maret W, Sandstead HH. Zinc requirements and the risks and benefits of zinc supplementation. J Trace Elem Med Biol 2006;20:3-18. [PubMed abstract]

Rink L, Gabriel P. Zinc and the immune system. Proc Nutr Soc 2000;59:541-52. [PubMed abstract]


World Health Organization. Iron Deficiency Anaemia: Assessment, Prevention, and Controlexternal link disclaimer. World Health Organization, 2001.

Powers JM, Buchanan GR. Disorders of iron metabolism: New diagnostic and treatment approaches to iron deficiency. Hematol Oncol Clin North Am. 2019 Jun;33(3):393-408.

Powers JM, Buchanan GR. Disorders of iron metabolism: New diagnostic and treatment approaches to iron deficiency. Hematol Oncol Clin North Am. 2019 Jun;33(3):393-408. [PubMed abstract]


Institute of Medicine. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC; 2005

Stone MS, Martyn L, Weaver CM. Potassium intake, bioavailability, hypertension, and glucose control. Nutrients 2016;8. [PubMed abstract]

Preuss HG, Clouatre DL. Sodium, chloride, and potassium. In: Erdman JW, Macdonald IA, Zeisel SH, eds. Present Knowledge in Nutrition. 10th ed. Washington, DC: Wiley-Blackwell; 2012:475-92.


Gonzalez-Ortiz M, Martinez-Abundis E, Robles-Cervantes JA, Ramirez-Ramirez V, Ramos-Zavala MG. Effect of thiamine administration on metabolic profile, cytokines and inflammatory markers in drug-naive patients with type 2 diabetes. Eur J Nutr 2011;50:145-9. [PubMed abstract]

Alaei Shahmiri F, Soares MJ, Zhao Y, Sherriff J. High-dose thiamine supplementation improves glucose tolerance in hyperglycemic individuals: a randomized, double-blind cross-over trial. Eur J Nutr 2013;52:1821-4. [PubMed abstract]

Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116:600-5. [PubMed abstract]

Vitamin E

Sesso HD, Buring JE, Christen WG, Kurth T, Belanger C, MacFadyen J, et al. Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians’ Health Study II randomized controlled trial. JAMA 2008;300:2123-33. [PubMed abstract]

Blumberg JB, Frei B. Why clinical trials of vitamin E and cardiovascular diseases may be fatally flawed. Commentary on “The relationship between dose of vitamin E and suppression of oxidative stress in humans.” Free Radic Biol Med 2007;43:1374-6. [PubMed abstract]

Weitberg AB, Corvese D. Effect of vitamin E and beta-carotene on DNA strand breakage induced by tobacco-specific nitrosamines and stimulated human phagocytes. J Exp Clin Cancer Res 1997;16:11-4. [PubMed abstract]


Massey LK, Whiting SJ. Caffeine, urinary calcium, calcium metabolism, and bone. J Nutr 1993;123:1611-4. [PubMed abstract]

Hirsch PE, Peng TC. Effects of alcohol on calcium homeostasis and bone. In: Anderson J, Garner S, eds. Calcium and Phosphorus in Health and Disease. Boca Raton, FL: CRC Press, 1996:289-300.

Calvo MS. Dietary phosphorus, calcium metabolism and bone. J Nutr 1993;123:1627-33. [PubMed abstract]


Friedli N, Stanga Z, Culkin A, et al. Management and prevention of refeeding syndrome in medical inpatients: An evidence-based and consensus-supported algorithm. Nutrition 2018;47:13-20. [PubMed abstract]

Moe SM, Drüeke T, Lameire N, Eknoyan G. Chronic kidney disease–mineral-bone disorder: a new paradigm. Advances in Chronic Kidney Disease 2007;14:3-12. [PubMed abstract]

Liu Z, Su G, Guo X, et al. Dietary interventions for mineral and bone disorder in people with chronic kidney disease. Cochrane Database Syst Rev 2015:Cd010350. [PubMed abstract]

Vitamine K

Schurgers LJ. Vitamin K: key vitamin in controlling vascular calcification in chronic kidney disease. Kidney Int2013;83:782-4. [PubMed abstract]

Shearer MJ, Fu X, Booth SL. Vitamin K nutrition, metabolism, and requirements: current concepts and future research. Adv Nutr 2012;3:182-95. [PubMed abstract]

Shearer MJ, Newman P. Metabolism and cell biology of vitamin K. Thromb Haemost 2008;100:530-47. [PubMed abstract]


Patrick L. Iodine: deficiency and therapeutic considerations. Altern Med Rev. 2008 Jun;13(2):116-127. [PubMed abstract]

Zimmermann MB. Iodine deficiency. Endocr Rev. 2009 Jun;30(4):376-408. [PubMed abstract]

Zimmermann MB, Jooste PL, Pandav CS. Iodine-deficiency disorders. Lancet. 2008 Oct 4;372(9645):1251-1262. [PubMed abstract]

Vitamine B6

Merrill AH, Jr., Henderson JM. Diseases associated with defects in vitamin B6 metabolism or utilization. Annu Rev Nutr 1987;7:137-56. [PubMed abstract]

Chiang EP, Selhub J, Bagley PJ, Dallal G, Roubenoff R. Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. Arthritis Res Ther 2005;7:R1404-11. [PubMed abstract]

Ebbing M, Bonaa KH, Arnesen E, Ueland PM, Nordrehaug JE, Rasmussen K, et al. Combined analyses and extended follow-up of two randomized controlled homocysteine-lowering B-vitamin trials. J Intern Med 2010;268:367-82. [PubMed abstract]


McKenney J. New perspectives on the use of niacin in the treatment of lipid disorders. Arch Intern Med 2004;164:697-705. [PubMed abstract]

Jacobson EL, Jacobson MK Tissue NAD as a biochemical measure of niacin status in humans. Methods in Enzymology 1997;280:221-30.

MacKay D, Hathcock J, Guarneri. Niacin: chemical forms, bioavailability, and health effects. Nutr Rev 2012;70:357-66

Vitamine C

Li Y, Schellhorn HE. New developments and novel therapeutic perspectives for vitamin C. J Nutr 2007;137:2171-84. [PubMed abstract]

Carr AC, Frei B. Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Am J Clin Nutr 1999;69:1086-107. [PubMed abstract]

Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci U S A 1989;86:6377-81. [PubMed abstract]

Jacob RA, Sotoudeh G. Vitamin C function and status in chronic disease. Nutr Clin Care 2002;5:66-74.

Riboflavine oftewel Vitamine B2

Di Lorenzo C, Pierelli F, Coppola G, Grieco GS, Rengo C, Ciccolella M, et al. Mitochondrial DNA haplogroups influence the therapeutic response to riboflavin in migraineurs. Neurology 2009;72:1588-94. [PubMed abstract]

Rivlin RS. Riboflavin. In: Coates PM, Betz JM, Blackman MR, et al., eds. Encyclopedia of Dietary Supplements. 2nd ed. London and New York: Informa Healthcare; 2010:691-9.


Carmel R. Folic acid. In: Shils M, Shike M, Ross A, Caballero B, Cousins RJ, eds. Modern Nutrition in Health and Disease. 11th ed. Baltimore, MD: Lippincott Williams & Wilkins; 2005:470-81.

Paniz C, Bertinato JF, Lucena MR, et al. A daily dose of 5 mg folic acid for 90 days is associated with increased serum unmetabolized folic acid and reduced natural killer cell cytotoxicity in healthy Brazilian adults. J Nutr 2017;147:1677-85.

Pantotheenzuur oftewel Vitamine B5

Hayflick SJ. Defective pantothenate metabolism and neurodegeneration. Biochem Soc Trans 2014;42:1063-8. [PubMed abstract]

Rumberger JA, Napolitano J, Azumano I, et al. Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk North American subjects: a triple-blinded placebo and diet-controlled investigation. Nutr Res 2011;31:608-15

Kelly GS. Pantothenic acid. Altern Med Rev 2011;16:263-74.

Vitamine A

O’Neil C, Shevill E, Chang AB. Vitamin A supplementation for cystic fibrosis. Cochrane Database Syst Rev 2010:CD006751.pub2. [PubMed abstract]

Borowitz D, Baker RD, Stallings V. Consensus report on nutrition for pediatric patients with cystic fibrosis. J Pediatr Gastroenterol Nutr 2002;35:246-59.


Rayman MP. Food-chain selenium and human health: emphasis on intake. Br J Nutr 2008;100:254-68. [PubMed abstract]

Rayman MP. Selenium and human health. Lancet 2012;379:1256-68. [PubMed abstract]

Flores-Mateo G, Navas-Acien A, Pastor-Barriuso R, Guallar E. Selenium and coronary heart disease: a meta-analysis. Am J Clin Nutr 2006;84:762-73. [PubMed abstract]

Vitamine D

Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81.

Wolpowitz D, Gilchrest BA. The vitamin D questions: how much do you need and how should you get it? J Am Acad Dermatol 2006;54:301-17.

de Sevaux RGL, Hoitsma AJ, Corstens FHM, Wetzels JFM. Treatment with vitamin D and calcium reduces bone loss after renal transplantation: a randomized study. J Am Soc Nephrol 2002;13:1608-14